PROPRANOLOL ADMINISTRATION IN INFANCY

Nasal Administration of Propranolol

Propranolol for severe hemangiomas of infancy.

n engl j med 358;24 www.nejm.org june 12, 2008 2649 negative predictive value.1 It should be noted that plasma levels of imatinib in patients given high doses of the drug exceed those of the no­effect level in the study of rat fertility. We also disagree with the specific reservations expressed by the correspondents. The time relationship was rea­ sonable, with oligomenorrhea occurring a few mo...

Propranolol treatment for hemangioma of infancy.

Infantile hemangioma or hamangioma of infancy is the most common tumor in children, with great variability of presentation. Most cases resolve spontaneously and treatment is usually indicated for specific cases where injury has a high rate of morbidity or disfigurement after regression. The treatment is based on the use of systemic corticosteroids, which can also be used topically or by intrale...

Re: Propranolol treatment for hemangioma of infancy: risks and recommendations.

Hemangioma of infancy is a condition that may be associated with significant morbidity. While evidence most supports the use of corticosteroids, there is no well-defined or Federal Drug Administration (FDA)-approved systemic therapy for hemangioma of infancy. All currently used treatments have significant risks. Dramatic improvement of complicated hemangioma of infancy to propranolol was recent...

[Past, present, and future of propranolol for hemangiomas of infancy].

Hemangiomas of infancy are the most common vascular tumors of childhood, affecting 10% of newborns, especially females. Hemangiomas are biologically unique, and unlike other proliferative lesions, they tend to regress and resolve spontaneously through mechanisms involving intracellular events or signals that are still only partially understood. In many cases, a wait-and-see approach is therefor...